CompletedNot Applicable

Treatment of Hypertrophic Scars Using Fractional CO2 Laser Alone in Comparison With Adding Botulinum Toxin Either Through Intralesional Injection or Assisted Drug Delivery

Egypt48 participantsStarted 2025-01-01

Plain-language summary

The current study aimed to evaluate the effectiveness of fractional laser treatment alone and fractional laser combined with botulinum toxin A, delivered either through injections or topical application fractional laser-assisted drug delivery (FLADD) in hypertrophic burn scar

Who can participate

Age range18 Years – 70 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion criteria

✓. Scar Type: Clinically diagnosed hypertrophic burn scar not less than 4.5 cm
✓. Minimum Scar Size: 4.5cm x 1 cm
✓. Scar duration: At least 1 month old and not exceed 6 months.
✓. Fitzpatrick Skin Type: II to IV
✓. No Recent Scar Treatment: No scar treatment within the past 6 months
✓. Healthy Skin: No active skin infections in the treatment area
✓. Normal Neuromuscular Function: No history of neuromuscular disorders or medications affecting muscle function.

What they're measuring

Change in total Patient and Observer Scar Assessment Scale (POSAS) score for each scar section

Timeframe: Baseline and 3 months after the last treatment session

Change in Vancouver Scar Scale (VSS) total score

Timeframe: Baseline and 3 months after the last treatment session.

Trial details

NCT IDNCT07360483

SponsorCairo University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2025-05-01

View on ClinicalTrials.gov More Hypertrophic Scars trials