RecruitingNot Applicable

Microneedling With Platelet Rich Plasma Versus Microneedling Alone For Gingival Depigmentation

Egypt32 participantsStarted 2025-10-01

Plain-language summary

To evaluate the usage of microneedling with platelet rich plasma as a gingival depigmentation method in comparison to microneedling alone for pigment intensity reduction. Pre-operative preparation phase includes ultrasonic scaling and oral hygiene instructions for all patients. Eligible patients will be randomly allocated into two groups. Clinical photographs: Clinical photographs will be taken at baseline, 1 and 6 months postoperatively. Intervention Group (Group A): Microneedling will be done with application of Platelet Rich Plasma for depigmentation. Control Group (Group B): microneedling will be done alone for depigmentation.

Who can participate

Age range18 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * • Patients exhibiting melanin hyperpigmentation in the anterior region of the upper or lower gingiva. * Age ≥ 18 year old. * Patients should be free from any systemic diseases according to modified Cornell Medical index (Abramson 1966). * Non- smokers Exclusion Criteria: * • Fully edentulous patients. * Patients with endocrine disorders causing hyperpigmentation or drug induced gingival pigmentation. (Sreeja, Ramakrishnan et al. 2015) * Pregnant or lactating females.

What they're measuring

Dummett-Gupta Oral Pigmentation Index (DOPI)

Timeframe: 6 months

Trial details

NCT IDNCT07359339

SponsorCairo University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2026-09-30

View on ClinicalTrials.gov More Gingival Pigmentation trials