Active — Not RecruitingNot Applicable

CPAP Therapy and Atrial Fibrillation Recurrence in OSA

Bulgaria91 participantsStarted 2024-09-01

Plain-language summary

Obstructive sleep apnea (OSA) is a major modifiable risk factor for atrial fibrillation (AF). Continuous positive airway pressure (CPAP) therapy has been shown to improve cardiovascular outcomes; however, real-world data on its effect on AF recurrence remain limited. This prospective cohort study aims to evaluate the association between objective CPAP adherence and the risk of AF recurrence in patients with moderate-to-severe OSA and a history of paroxysmal AF. Patients will be followed for 12 months, with AF recurrence assessed using electrocardiography and Holter monitoring.

Who can participate

Age range18 Years

SexALL

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Inclusion criteria

✓. Age ≥ 18 years
✓. Diagnosed moderate-to-severe OSA
✓. History of paroxysmal atrial fibrillation
✓. Ability to initiate CPAP therapy
✓. Written informed consent -

Exclusion criteria

✕. Left ventricular ejection fraction \< 50%
✕. Permanent atrial fibrillation
✕. Central sleep apnea
✕. End-stage chronic kidney disease
✕. Inability to obtain or tolerate CPAP therapy -

What they're measuring

Time to First Recurrence of Paroxysmal Atrial Fibrillation

Timeframe: 12 months

Trial details

NCT IDNCT07358429

SponsorMedical University of Sofia

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2025-11-30

View on ClinicalTrials.gov More Obstructive Sleep Apnea (OSA) trials