By InvitationNot Applicable

Prospective Familial Registry for Pancreas Research

United States3,000 participantsStarted 2026-01-05

Plain-language summary

The purpose of this research is to develop a resource registry of individuals currently without pancreatic cancer but are members of a kindred with two or more blood-related family members with pancreas cancer.

Who can participate

Age range18 Years

SexALL

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Inclusion criteria

✓. An individual who was previously enrolled in Mayo Clinic IRB # 1197-00, 354-06, 355-06, or 19-010791
✓. Is age 18 years or older.
✓. Has a valid United States mailing address.
✓. Has at least two blood-related relatives who have had pancreas cancer or has a blood-relative with pancreatic cancer and that relative carries a known germline mutation in APC, ATM, BRCA1, BRCA2, CDKN2A, EPCAM, MLH1, MSH2, MSH6, PALB2, PMS2, STK11, TP53 or mutations in other genes known to be associated with pancreatic cancer.

Exclusion criteria

✕. An individual who is a prison inmate
✕. An individual who is not compos mentis (of sound mind, memory, and understanding), and not able to give consent.
✕. Has personal history of pancreas cancer.

What they're measuring

To establish a prospective cohort of individuals from pancreas cancer families

Timeframe: 25 years

Change in health

Timeframe: 25 years

Trial details

NCT IDNCT07358208

SponsorMayo Clinic

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2040-11

View on ClinicalTrials.gov More Family History of Pancreas Cancer trials