CompletedNot Applicable

Effect of Different Root Canal Disinfection Procedures on Postoperative Pain

Turkey (Türkiye)80 participantsStarted 2023-06-13

Plain-language summary

This clinical study evaluated the effects of different root canal disinfection procedures on postoperative pain. Patients requiring root canal treatment received one of several disinfection methods. Postoperative pain was assessed at 6,24, 48, 72 hours and on the 7th day using a standard pain scale. The aim of the study was to identify which method resulted in the least discomfort. Participation involved a single treatment session and short-term follow-up for pain measurement.

Who can participate

Age range

18 Years – 65 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion criteria * Systemically healthy individuals between the ages of 18 and 65, * Adequate mouth opening, * Asymptomatic devitaled mandibular premolar with a single root and single canal, * Negative response to cold and electric pulp tests and no bleeding at the pulp chamber opening, * Able to provide rubber dam isolation, * Presence of opposing teeth. Exclusion criteria * Presence of mental or psychiatric disorders, * Allergic diseases, * Use of painkillers within 12 hours or antibiotics within 1 week before the procedure, * Swelling, palpation/percussion pain, or sinus tract before treatment, * Presence of a periodontal pocket greater than 3 mm in diameter on the involved tooth, * Presence of a periapical radiolucency greater than 5 mm in diameter associated with the involved tooth, * Initiation of root canal treatment, * Irreparable material loss, root fracture, or crack, * Severe mobility, * Open apex, * Severe root canal calcification, * Internal or external resorption, * Bruxism, * Complaints of pain elsewhere in the mouth or in a tooth, * Being pregnant or breastfeeding.

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

Postoperative Pain Intensity

Timeframe: 6, 12, 24, 48, and 72 hours after root canal treatment

Trial details

NCT IDNCT07355816

SponsorCumhuriyet University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2024-11-11

View on ClinicalTrials.gov More Pain, Postoperative trials