Effect of Different Root Canal Disinfection Procedures on Postoperative Pain

Inclusion criteria * Systemically healthy individuals between the ages of 18 and 65, * Adequate mouth opening, * Asymptomatic devitaled mandibular premolar with a single root and single canal, * Negative response to cold and electric pulp tests and no bleeding at the pulp chamber opening, * Able to provide rubber dam isolation, * Presence of opposing teeth. Exclusion criteria * Presence of mental or psychiatric disorders, * Allergic diseases, * Use of painkillers within 12 hours or antibiotics within 1 week before the procedure, * Swelling, palpation/percussion pain, or sinus tract before treatment, * Presence of a periodontal pocket greater than 3 mm in diameter on the involved tooth, * Presence of a periapical radiolucency greater than 5 mm in diameter associated with the involved tooth, * Initiation of root canal treatment, * Irreparable material loss, root fracture, or crack, * Severe mobility, * Open apex, * Severe root canal calcification, * Internal or external resorption, * Bruxism, * Complaints of pain elsewhere in the mouth or in a tooth, * Being pregnant or breastfeeding.