RecruitingNot Applicable

Hybrid Group Singing

United States32 participantsStarted 2026-04

Plain-language summary

The overall objective of the planned future clinical trial is to test the investigator's central hypothesis that habitual singing over several weeks, similar to habitual exercise, will lead to sustained and favorable vascular adaptation, thereby lowering cardiovascular disease (CVD) risk. The overall objective of this study is to refine and protocolize the singing interventions and test the feasibility of the future trial design. The investigative team has previously studied solo singing. Collective singing, as in a choir or small group, is associated with a positive sense of social inclusion, well-being, and improved mood, including in older adults.

Who can participate

Age range55 Years – 89 Years

SexALL

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Inclusion Criteria: * history of coronary artery disease (defined as having at least 1 of the following: myocardial infarction, coronary stent, PCI, CABG, coronary stenosis at least 50%, or coronary artery calcification score at least 300 Agatston units) Exclusion Criteria: * Parkinson's disease or tremor * upper arm fistula * fingernail onychomycosis * pregnancy * current tobacco use * current illicit drug use * current excessive alcohol use (defined as more than 14 drinks/week for women, more than 28 drinks/week for men) * unstable CAD (active symptoms of chest discomfort) * supplemental oxygen use * more than mild cognitive impairment (as documented in the medical record by patient's treatment teams) * inability to follow study procedures * non-English speaking

What they're measuring

Adherence

Timeframe: 12 weeks

Trial details

NCT IDNCT07355192

SponsorMedical College of Wisconsin

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2028-02

View on ClinicalTrials.gov More Coronary Artery Disease trials