Pneumococcal Community-Acquired Pneumonia Requiring Hospitalization Among Colombian Adults

Inclusion Criteria: * (1) Age ≥ 18 years old. * (2) Hospitalized at one of the hospitals of Sabana Centro Region, including both in-patient and observation status stay. * (3) Clinical signs and/or symptoms of an acute respiratory illness, as defined by ≥ 1 of the * following: * -New or worsening shortness of breath in the past 7 days * -New or worsening cough in the past 7 days * -New or worsening sputum production in the past 7 days * -New or worsening chest pain in the past 7 days * -Tachypnea to respiratory rate ≥ 22 breaths/min, not known to be chronic * -Hypoxia to SpO2 ≤ 92% not known to be chronic * -Initiation of invasive or non-invasive mechanical ventilation * (4) Clinical signs and/or symptoms of an acute infection, as defined by ≥ 1 of the following: * -Body temperature ≥ 38º C (100.4º F) or ≤ 35.5º C (95.9º F) * -Reported fever, chills, or feeling feverish at home without explicit documentation of a fever within the past 7 days * -White blood cell count \> 10.7 or \< 3.9 thousand cells/mcL-C-reactive protein \> 10 mg/L * -Altered mental status * (5) Radiologic evidence of pneumonia interpreted by a radiologist, defined as ≥ 1 of the following findings on chest x-ray (CXR), computed tomography (CT), or lung ultrasound completed within 48 hours before or after hospital admission: * -Pulmonary infiltrate not known to be chronic * -Pulmonary opacity is not known to be chronic (including ground-glass opacities on CT) * -Pulmonary consolidation is not known to be Exc…