By InvitationNot Applicable

Low-Intensity Focused Ultrasound Neuromodulation for Epilepsy

United States6 participantsStarted 2025-10-13

Plain-language summary

This study is an invite only study looking at the effects of Low-Intensity Focused Ultrasound (LIFU) on epilepsy patients with implanted electrodes under the care of Dr. Shah.

Who can participate

Age range18 Years – 85 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Diagnosis of medically refractory focal epilepsy of mesial temporal onset * RNS system implantation in the hippocampus * Prior MRI and CT of the head * Able to consent for themselves * Internet access Exclusion Criteria: * TBI (ongoing, or in the prior 6 months) * Currently pregnant or breastfeeding * Progressive diseases - such as autoimmune epilepsies or diagnosis of a progressive neurological disorder * Status epilepticus within one year of study start * History of suicidal ideation or attempts in the last 6 months

What they're measuring

Seizure Frequency

Timeframe: 6 months past their final research study visit

Trial details

NCT IDNCT07353918

SponsorCarilion Clinic

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2027-12

View on ClinicalTrials.gov More Epilepsy (Treatment Refractory) trials