Not Yet RecruitingNot Applicable

Vocal Fold Injection by Platelet Rich Plasma

Egypt48 participantsStarted 2025-12-29

Plain-language summary

a study to asses safety and efficacy of platelet rich plasma injection in some types of vocal fold problems such as sulcus and atrophy to see the improvement in patient voice and its impact on patient quality of life with a good period of follow up

Who can participate

Age range10 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * 1-Age ≥ 10 years 2-Gender: both sexes will be included in the study 3-clinical diagnosis of vocal fold sulcus, scar or atrophy. 4-Diagnosis confirmed by video laryngoscope examination. 5-be able to participate and sign informed consent. Exclusion Criteria: 1- Laryngeal cancer. 2. Acute laryngeal infection . 3. Systemic diseases that may impair healing, such as:(Uncontrolled diabetes mellitus-Autoimmune disorders affecting the larynx-Coagulopathy or bleeding disorders). 4\. Use of systemic corticosteroids or immunosuppressive drugs within the last 4 weeks. 5\. Previous laryngeal surgery within the last 6 months 6. Pregnancy or lactation. 7. Known allergy or hypersensitivity to local anesthetics or any component used in PRP preparation. 8\. Inability to complete with follow-up visits or voice assessment protocols

What they're measuring

1-Subjective assessment of the patient using GRBAS scale 2- Subjective assessment of the patien by Arabic version of VHI •3- objective assessment of the patient using video stereoscopic examination and Acoustic analysis • 4-Improvement of patient voice

Timeframe: 4 years

Trial details

NCT IDNCT07350642

SponsorAssiut University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2029-06

Contact for this trial

Aya Essam Sheakawy Essam Aya Shrakawy, Assistant lecture

+2 01008137079 dr.aya.elsharkawy93@gmail.com

View on ClinicalTrials.gov More Vocal Fold Sulcus ,Scar and Atrophy trials

Who can participate

Age range10 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.