The general objective of this observational study is to clarify the clinical, microbial, and tissue characteristics, aetiology, and risk factors behind severe TMJ pathology. The main questions it aims to answer are: * What are the clinical and histologic characteristics of patients with severe pathology of the TMJ? * Can microbial DNA be found in TMJ tissue from patients with severe pathology of the TMJ, and if so, does this correlate to the outcome of the surgery?
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Clinical investigation (patients):
Timeframe: Inclusion will take at least 3 years, followed by one year of follow-up
Questionnaires:
Timeframe: Inclusion will take at least 3 years, followed by one year of follow-up.
Histopathologic analyses:
Timeframe: 3 years
Analysis of microbial DNA in the Biobank material using 16S metagenomic sequencing
Timeframe: 3 years
Objective & Subjective measurements
Timeframe: Inclusion will take at least 3 years. Then one year follow up
Objective and subjective measurments
Timeframe: Inclusion will take at least 3 years. Then one year follow up
Objective and subjective measurments
Timeframe: Inclusion will take at least 3 years. Then one year follow up
Objective and subjective measurments
Timeframe: Inclusion will take at least 3 years. Then one year follow up
Objective and subjective measurments
Timeframe: Inclusion will take at least 3 years. Then one year follow up
Objective and subjective measurments
Timeframe: Inclusion will take at least 3 years. Then one year follow up
Objective and subjective measurments
Timeframe: Inclusion will take at least 3 years. Then one year follow up