The general objective of this observational study is to clarify the clinical, microbial, and tissue characteristics, aetiology, and risk factors behind severe TMJ pathology. The main questions it aims to answer are: * What are the clinical and histologic characteristics of patients with severe pathology of the TMJ? * Can microbial DNA be found in TMJ tissue from patients with severe pathology of the TMJ, and if so, does this correlate to the outcome of the surgery?
Age range
18 Years
Sex
ALL
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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
Clinical investigation (patients):
Timeframe: Inclusion will take at least 3 years, followed by one year of follow-up
Questionnaires:
Timeframe: Inclusion will take at least 3 years, followed by one year of follow-up.
Histopathologic analyses:
Timeframe: 3 years
Analysis of microbial DNA in the Biobank material using 16S metagenomic sequencing
Timeframe: 3 years
Objective & Subjective measurements
Timeframe: Inclusion will take at least 3 years. Then one year follow up
Objective and subjective measurments
Timeframe: Inclusion will take at least 3 years. Then one year follow up
Objective and subjective measurments
Timeframe: Inclusion will take at least 3 years. Then one year follow up
Objective and subjective measurments
Timeframe: Inclusion will take at least 3 years. Then one year follow up
Objective and subjective measurments
Timeframe: Inclusion will take at least 3 years. Then one year follow up
Objective and subjective measurments
Timeframe: Inclusion will take at least 3 years. Then one year follow up
Objective and subjective measurments
Timeframe: Inclusion will take at least 3 years. Then one year follow up