Effects of Trophectoderm (TE) Biopsy on the Health and Development of Children Born After Preimpl… (NCT07349966) | Clinical Trial Compass
By InvitationNot Applicable
Effects of Trophectoderm (TE) Biopsy on the Health and Development of Children Born After Preimplantation Genetic Testing (PGT) Cycles.
Italy330 participantsStarted 2026-03-19
Plain-language summary
This study aims to investigate the effects of trophectoderm (TE) biopsy on the health and development of children born after preimplantation genetic testing (PGT) cycles. The blastocyst biopsy is performed as part of standard clinical practice, in accordance with established protocols and current national regulations governing assisted reproduction.
Who can participate
Age range
60 Months
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria for Cases:
* Child: Has completed the first year of life at the time of data collection.
* Child: Does not have any pre-existing medical conditions that significantly affect growth (weight and height).
* Mother: Able to provide informed consent for participation in the study.
* Mother: Conceived between the ages of 18 and 43.
* Mother: Achieved a singleton live birth with a single gestational sac.
* Mother: Underwent a PGT cycle followed by FET.
Inclusion Criteria for Controls:
* Child: Has completed the first year of life at the time of data collection.
* Child: Does not have any pre-existing medical conditions that significantly affect growth (weight and height).
* Mother: Able to provide informed consent for participation in the study.
* Mother: Conceived between the ages of 18 and 43.
* Mother: Achieved a singleton live birth with a single gestational sac.
* Mother: Underwent only FET.
Participants will be excluded from this study if they meet any of the following criteria:
* Mother: Unable or unwilling to sign the informed consent.
* Mother: Has undergone a fresh embryo transfer.
* Child: Missing birth weight or length/height data.
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Impact of Blastocyst Biopsy on Postnatal Growth at One Year