RecruitingNot Applicable

Comparative Study of Functional Outcomes Between Peroneus Longus and Hamstring Tendon Autografts in Arthroscopic ACL Reconstruction

Pakistan64 participantsStarted 2026-01-01

Plain-language summary

This is a prospective, single-blinded, randomized controlled trial. Sixty patients (≥18 years) with an isolated ACL injury will be randomly assigned to receive an ACL reconstruction using either a Peroneus Longus Tendon (PLT) autograft or a Hamstring Tendon (HST) autograft. The primary objective is to compare early functional outcomes between the two groups at 6 weeks and 3 months post-surgery, using the Lysholm Knee Score. The study aims to demonstrate the non-inferiority of the PLT graft. All surgeries will be performed arthroscopically at Khyber Teaching Hospital, Peshawar, followed by a standardized rehabilitation protocol.

Who can participate

Age range18 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Patients aged 18 years or older. * Isolated, primary Anterior Cruciate Ligament (ACL) injury confirmed by clinical assessment and Magnetic Resonance Imaging (MRI). * Provides written informed consent for the surgical procedure and study participation, including follow-up assessments. Exclusion Criteria: * Multiligament knee injuries (e.g., concomitant PCL, MCL, or LCL injuries). * Previous surgery or history of fracture in the involved lower limb. * Radiographic evidence of osteoarthritis in the affected knee. * Presence of any neuromuscular disease.

What they're measuring

Knee instability

Timeframe: 6 weeks, 3 months after surgery

Knee function

Timeframe: 6 weeks, 3 months after surgery

Trial details

NCT IDNCT07346326

SponsorKhyber Medical University Peshawar

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2026-07-28

Contact for this trial

Dr Syed Dil Bagh Ali Shah, MBBS

+92-91-9217701 drdilbagh@icloud.com