Not Yet RecruitingPhase 3

Comparison of Quadratus Lumborum and Combined Groin Nerve Blocks for Postoperative Analgesia After Open Inguinal Hernia Repair.

Egypt66 participantsStarted 2026-01-28

Plain-language summary

This double-blind randomized controlled trial aimes to compares two ultrasound-guided regional techniques-lateral quadratus lumborum block versus combined ilio-inguinal/ilio-hypogastric/genitofemoral (II-IH-GFN) block-for postoperative analgesia after elective unilateral open inguinal hernia repair under spinal anesthesia in adults.

Who can participate

Age range

18 Years – 75 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Adults aged 18-75 years. * ASA physical status I-III. * Scheduled for elective unilateral open inguinal hernia repair under standardized spinal anesthesia. * Able to understand and use the Visual Analogue Scale (VAS). * Provided written informed consent. Exclusion Criteria: * Allergy to local anesthetics. * Coagulopathy or current use of anticoagulants contraindicating peripheral nerve blocks. * Infection at the injection site. * Chronic opioid use (daily opioids \>2 weeks) or chronic pain syndromes. * Body mass index (BMI) \>40 kg/m². * Conversion to other surgery or bilateral repair. * Pregnant patients. * Refusal to sign informed consent.

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

Cumulative opioid consumption in the first 24 hours postoperatively

Timeframe: 24 hours after surgery.

Trial details

NCT IDNCT07343570

SponsorAl-Azhar University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2026-11-30

Contact for this trial

Neveen A. Kohaf, Ph.D

01060383012 nevenabdo@azhar.edu.eg

View on ClinicalTrials.gov More Postoperative Analgesia of Inguinal Hernia Repair in Adults trials