Decreasing Edema With a Novel OCS Solution Trial

Donor Inclusion/Exclusion Criteria Inclusion Criteria: * Donor lungs are deemed clinically acceptable for transplantation after physical examination of the donor lungs in the donor and/or on the back table in the donor operating room. * Eligible for randomization to OCS or SCS treatment arms. Exclusion Criteria: \- Severe traumatic donor lung injury with air and/or blood leak (as seen on radiological studies, bronchial examinations or final visual physical assessment in donor's chest or back table). Recipient Inclusion/Exclusion: Inclusion Criteria: * Signed informed consent document and authorization to use and disclose protected health information * Double lung transplant candidate * Age ≥ 18 years old Exclusion: \- Participant in any other interventional clinical or investigational trials/programs that may confound the outcomes of this trial.