RecruitingNot Applicable

Dose-Finding Study: MEV90 for Local Anesthetic in Interscalene Block for Supraclavicular Nerves Block

Chile55 participantsStarted 2026-04

Plain-language summary

This study aims to determine the minimum effective volume (MEV90) of local anesthetic required to achieve sensory block of the supraclavicular nerves when performing a single-shot ultrasound-guided interscalene brachial plexus block (ISB). These nerves provide sensation to the skin over the clavicle and shoulder and are often involved in surgeries such as shoulder arthroscopy and clavicle repair.

Who can participate

Age range

18 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Age ≥ 18 years * ASA physical status I to III * Body Mass Index (BMI) between 18 and 35 kg/m² * Weight ≥ 50 kg * Scheduled for shoulder arthroscopy requiring an interscalene brachial plexus block for analgesia * Able to provide informed consent Exclusion Criteria: * Inability to provide informed consent * Coagulopathy (platelet count ≤100,000; INR ≥1.4) * Significant pulmonary disease (restrictive or obstructive) * Renal insufficiency (creatinine ≥1.2 mg/dL) * Hepatic insufficiency (transaminases ≥100 U/L) * Allergy to local anesthetics * Pregnancy * Pre-existing neuropathy * Previous surgery in ipsilateral cervical or supraclavicular region * Contralateral hemidiaphragmatic paralysis or vocal cord paralysis

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

Minimum Effective Volume (MEV90) for Supraclavicular Nerve Block via Interscalene Approach

Timeframe: 30 minutes after completion of the block

Trial details

NCT IDNCT07338916

SponsorHospital del Trabajador de Santiago

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2026-11

Contact for this trial

Germán Aguilera, MD

+56985205514 german.aguilera@gmail.com

View on ClinicalTrials.gov More Brachial Plexus Blockade trials