CompletedPhase 4

Effect of IV Lidocaine on Duodenal Peristalsis and Sedation in ERCP

Turkey (Türkiye)120 participantsStarted 2026-02-11

Plain-language summary

This study aims to evaluate the efficacy of intravenous lidocaine infusion on duodenal peristalsis during Endoscopic Retrograde Cholangiopancreatography (ERCP). The study compares lidocaine against a placebo to determine if lidocaine can reduce the need for rescue spasmolytics (hyoscine-N-butylbromide or glucagon), decrease propofol consumption, and improve hemodynamic stability.

Who can participate

Age range18 Years – 85 Years

SexALL

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Inclusion Criteria: * Patients scheduled for elective ERCP. ASA Physical Status I, II, or III. Age between 18 and 85 years. Provided written informed consent. Exclusion Criteria: * Allergy to amide-type local anesthetics. Severe hepatic or renal failure. History of AV block or severe cardiac arrhythmia. Pregnancy or lactation. Chronic opioid use. Patient refusal.

What they're measuring

Rescue Spasmolytic Requirement Rate

Timeframe: Intraoperative (During the ERCP procedure, approx. 30 minutes)

Trial details

NCT IDNCT07333859

SponsorAnkara City Hospital Bilkent

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2026-02-11

View on ClinicalTrials.gov More Duodenal Spasm trials