CompletedNot Applicable

Effects of Marching Exercise With Cognitive Training on Physical, Cognitive Function, and Autonomic Cardiovascular Responses in Older Adults With Type 2 Diabetes Mellitus

Thailand60 participantsStarted 2025-07-10

Plain-language summary

This study aims to evaluate the effects of a combined marching exercise with cognitive training program on physical performance, cognitive function, and autonomic cardiovascular responses in older adults with type 2 diabetes mellitus. Participants will be randomly assigned to either an intervention group receiving marching exercise with cognitive tasks or a control group receiving usual care. Outcomes will be assessed before and after the intervention period. The findings are expected to provide evidence for a feasible and safe exercise strategy to improve physical and cardiovascular health in older adults with type 2 diabetes.

Who can participate

Age range60 Years – 80 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion criteria

✓. Male and female.
✓. Aged between 60 and 79 years.
✓. Medically diagnosed with type 2 diabetes.
✓. Peripheral neuropathy with a score of 7 or higher according to the Michigan Neuropathy Screening Instrument (MNSI).
✓. Body Mass Index (BMI) within the normal range (between 18.5-24.5 kg/m²).
✓. Able to follow instructions and willing to participate in the study.
✓. Able to communicate with researchers and provide information independently (researchers will read the questions to the volunteers and allow them to choose their own answers).
✓. Able to walk continuously for at least 10 meters without the use of walking aids.

Exclusion criteria

✕. Neurological disease (e.g., stroke, Parkinson's disease, spinal cord injury) that affects mobility, such as balance and gait.

What they're measuring

Heart rate variability (HRV)

Timeframe: Baseline, immediately after 6 weeks of intervention, and 1-month follow-up

Handgrip strength test

Timeframe: Baseline, immediately after 6 weeks of intervention, and 1-month follow-up

Five times sit-to-stand test (FTSST)

Timeframe: Baseline, immediately after 6 weeks of intervention, and 1-month follow-up

Timed Up and Go Test (TUGT)

Timeframe: Baseline, immediately after 6 weeks of intervention, and 1-month follow-up

Static Balance Single-leg stance test (SLST)

Timeframe: Baseline, immediately after 6 weeks of intervention, and 1-month follow-up

6-minute walk test

Timeframe: Baseline, immediately after 6 weeks of intervention, and 1-month follow-up

Motor-Cognitive Dual-Task Test:

Timeframe: Baseline, immediately after 6 weeks of intervention, and 1-month follow-up

Trial details

NCT IDNCT07330700

SponsorChonticha Kaewjoho

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2025-11-05

View on ClinicalTrials.gov More Type2 Diabetes Mellitus trials

Plain-language summary

Who can participate

Age range60 Years – 80 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion criteria

✓. Male and female.
✓. Aged between 60 and 79 years.
✓. Medically diagnosed with type 2 diabetes.
✓. Peripheral neuropathy with a score of 7 or higher according to the Michigan Neuropathy Screening Instrument (MNSI).
✓. Body Mass Index (BMI) within the normal range (between 18.5-24.5 kg/m²).
✓. Able to follow instructions and willing to participate in the study.
✓. Able to communicate with researchers and provide information independently (researchers will read the questions to the volunteers and allow them to choose their own answers).
✓. Able to walk continuously for at least 10 meters without the use of walking aids.

Exclusion criteria

✕. Neurological disease (e.g., stroke, Parkinson's disease, spinal cord injury) that affects mobility, such as balance and gait.

What they're measuring

Heart rate variability (HRV)

Timeframe: Baseline, immediately after 6 weeks of intervention, and 1-month follow-up

Handgrip strength test

Timeframe: Baseline, immediately after 6 weeks of intervention, and 1-month follow-up

Five times sit-to-stand test (FTSST)

Timeframe: Baseline, immediately after 6 weeks of intervention, and 1-month follow-up

Timed Up and Go Test (TUGT)

Timeframe: Baseline, immediately after 6 weeks of intervention, and 1-month follow-up

Static Balance Single-leg stance test (SLST)

Timeframe: Baseline, immediately after 6 weeks of intervention, and 1-month follow-up

6-minute walk test

Timeframe: Baseline, immediately after 6 weeks of intervention, and 1-month follow-up

Motor-Cognitive Dual-Task Test:

Timeframe: Baseline, immediately after 6 weeks of intervention, and 1-month follow-up