Effects of Marching Exercise With Cognitive Training on Physical, Cognitive Function, and Autonom… (NCT07330700) | Clinical Trial Compass
CompletedNot Applicable
Effects of Marching Exercise With Cognitive Training on Physical, Cognitive Function, and Autonomic Cardiovascular Responses in Older Adults With Type 2 Diabetes Mellitus
Thailand60 participantsStarted 2025-07-10
Plain-language summary
This study aims to evaluate the effects of a combined marching exercise with cognitive training program on physical performance, cognitive function, and autonomic cardiovascular responses in older adults with type 2 diabetes mellitus. Participants will be randomly assigned to either an intervention group receiving marching exercise with cognitive tasks or a control group receiving usual care. Outcomes will be assessed before and after the intervention period. The findings are expected to provide evidence for a feasible and safe exercise strategy to improve physical and cardiovascular health in older adults with type 2 diabetes.
Who can participate
Age range
60 Years – 80 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion criteria
. Male and female.
. Aged between 60 and 79 years.
. Medically diagnosed with type 2 diabetes.
. Peripheral neuropathy with a score of 7 or higher according to the Michigan Neuropathy Screening Instrument (MNSI).
. Body Mass Index (BMI) within the normal range (between 18.5-24.5 kg/m²).
. Able to follow instructions and willing to participate in the study.
. Able to communicate with researchers and provide information independently (researchers will read the questions to the volunteers and allow them to choose their own answers).
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Heart rate variability (HRV)
Timeframe: Baseline, immediately after 6 weeks of intervention, and 1-month follow-up
2
Handgrip strength test
Timeframe: Baseline, immediately after 6 weeks of intervention, and 1-month follow-up
3
Five times sit-to-stand test (FTSST)
Timeframe: Baseline, immediately after 6 weeks of intervention, and 1-month follow-up
4
Timed Up and Go Test (TUGT)
Timeframe: Baseline, immediately after 6 weeks of intervention, and 1-month follow-up
5
Static Balance Single-leg stance test (SLST)
Timeframe: Baseline, immediately after 6 weeks of intervention, and 1-month follow-up
6
6-minute walk test
Timeframe: Baseline, immediately after 6 weeks of intervention, and 1-month follow-up
7
Motor-Cognitive Dual-Task Test:
Timeframe: Baseline, immediately after 6 weeks of intervention, and 1-month follow-up
. Able to walk continuously for at least 10 meters without the use of walking aids.
Exclusion criteria
. Neurological disease (e.g., stroke, Parkinson's disease, spinal cord injury) that affects mobility, such as balance and gait.
. Open wounds on the skin that affect weight-bearing while standing or walking. 1) Deformities or abnormalities of the extremities, or disabilities resulting from the loss of limbs that may affect the study.
8
Motor-Cognitive Dual-Task Test
Timeframe: Baseline, immediately after 6 weeks of intervention, and 1-month follow-up
9
Montreal Cognitive Assessment (MoCA)
Timeframe: Baseline, immediately after 6 weeks of intervention, and 1-month follow-up