CompletedNot Applicable

Nursing-Led Deep Vein Thrombosis Prevention in Neurosurgery

China1,286 participantsStarted 2021-01-01

Plain-language summary

The goal of this clinical trial is to see if a nurse-led program (early movement, leg-sleeve squeezes, and blood tests) can prevent dangerous leg blood clots in adults who have just had brain or spine surgery. Main questions it aims to answer: * Does the program lower the number of clots within 30 days after surgery? * Is the program safer and more accurate than the usual clot-risk score nurses already use? Researchers will compare patients who receive the nurse-led program with patients who receive standard hospital care. Participants will: * Be randomly assigned to one of the two groups. * Have regular leg ultrasounds to check for clots. * Wear a small activity tracker if they are in the nurse-led group.

Who can participate

Age range18 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria * Age ≥ 18 years * Any elective or emergency craniotomy, spinal, or other neurosurgical procedure * Expected post-operative hospital stay ≥ 3 days * Patient or legally authorized representative willing and able to give written informed consent Exclusion Criteria * Pre-operative ultrasound or imaging proven DVT or pulmonary embolism * Known hereditary bleeding disorder (e.g., hemophilia) or platelet count \< 50 × 10⁹/L * Chronic therapeutic anticoagulation (warfarin, DOAC, heparin) that cannot be safely stopped, or need for full-dose post-op anticoagulation * Severe liver disease (Child-Pugh class C) or eGFR \< 30 mL/min/1.73 m² * Life-limiting co-morbidity with expected survival \< 30 days * Pregnancy or breastfeeding * Current participation in another interventional VTE trial

What they're measuring

Incidence of objectively confirmed lower-extremity deep-vein thrombosis (DVT)

Timeframe: 30 days

Trial details

NCT IDNCT07330661

SponsorWest China Hospital

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2023-12-30