Clinical, Radiographic, and Digital Evaluation of the Effects of Autogenous Grafts on Peri-implan… (NCT07330609) | Clinical Trial Compass
Not Yet RecruitingNot Applicable
Clinical, Radiographic, and Digital Evaluation of the Effects of Autogenous Grafts on Peri-implant Mucosa
Turkey (Türkiye)30 participantsStarted 2026-02-02
Plain-language summary
This study aims to evaluate the effects of autogenous grafts harvested from different palatal regions on the peri-implant mucosa when applied during second-stage dental implant surgery.
Clinical, radiographic, and digital assessment methods will be used to investigate the early effects of these grafts on peri-implant mucosal width and thickness. In addition, peri-implant tissue health and patient-reported outcomes will be evaluated to compare the effectiveness of the grafting techniques in peri-implant soft tissue management.
Who can participate
Age range
18 Months
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Age over 18 years
* Systemically healthy patients
* Presence of premolar or molar tooth loss in the mandible
* Adequate mesiodistal and interocclusal space for implant and restoration placement
* At least four months elapsed since tooth extraction
* Alveolar bone width of at least 6 mm and sufficient alveolar bone height to allow implant placement without compromising anatomical structures
* Full-mouth plaque and bleeding scores less than 20%
* Presence of opposing teeth in occlusion
* Keratinized mucosa width in the relevant region less than 2 mm
* Keratinized mucosa thickness in the relevant region of 2 mm or less
* Presence of a healthy second premolar in the maxilla
* Provision of written informed consent and permission for the use of data for research purposes
Exclusion Criteria:
* Poor oral hygiene
* Uncontrolled periodontal disease
* Pregnancy or lactation at any stage of the study
* Uncontrolled diabetes mellitus
* Immunocompromised patients
* Previous radiotherapy to the head and neck region
* Diseases or medications affecting bone metabolism
* Antibiotic use within the three months prior to the procedure
* Smoking more than 10 cigarettes per day
* Pre- or simultaneous bone augmentation prior to implant placement
* Lack of primary stability at the time of implant placement
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Peri-implant Mucosal Thickness
Timeframe: Pre-operative and post-operative (before implant placement, 3rd month (second-stage implant surgery), 6th month after implant placement, and 12th month after prosthetic loading)