RecruitingNot Applicable

Nighttime Synchrony of Your Nutrition and Circadian Health

United States120 participantsStarted 2025-12-19

Plain-language summary

Sleep is an important factor for overall health. This study will see how different light exposure patterns and food intake impact a person's metabolism (how the body breaks down food) when sleeping is reduced. Participants will attend 6 to 8 in-person visits to the study clinic, including three overnight stays. People will complete surveys and medical tests. The study will last about 4 to 6 months.

Who can participate

Age range18 Years – 35 Years

SexALL

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Inclusion criteria

✓. Age: 18-35 years old; equal numbers of men and women
✓. Body Mass Index (BMI): 18.5-24.9 kg/m2
✓. Sleep Habits: habitual self-reported average total sleep time (TST) 7-9 hours per night for prior 6 months

Exclusion criteria

✕. Clinically diagnosed sleep disorder or apnea hypopnea index (AHI) ≥5
✕. Evidence of significant organ system dysfunction or disease (e.g., heart disease, diabetes)
✕. Fasting plasma glucose ≥100 mg/dL
✕. Major psychiatric illness (e.g., major depressive disorder)
✕. Cancer that has been in remission less than 5 years
✕. History of shift-work in prior year
✕. Weight change \>5% of body weight over prior six months
✕. Currently following a weight-loss program

What they're measuring

Insulin Sensitivity

Timeframe: Immediately following the 5-day sleep restriction segment

Internal Circadian Misalignment (Uridine and Isobutyryl-L-carnitine)

Timeframe: During the constant routine, following the 5-day sleep restriction segment

Trial details

NCT IDNCT07329283

SponsorUniversity of Utah

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2030-05-31

Contact for this trial

Victoria Miranda, MS

385-309-0551 SleepStudyParticipant@utah.edu

View on ClinicalTrials.gov More Sleep trials