The aim of this clinical study is to examine the effect of an 8-week training program applied to the respiratory muscles that enable breathing in individuals with obstructive sleep apnea syndrome on cognitive functions, oxygenation of brain tissue, and the brain's healing and adaptation processes. The main questions it aims to answer are: Does respiratory muscle training applied to individuals with obstructive sleep apnea syndrome have a beneficial effect on cognitive functions? Does respiratory muscle training applied to individuals with obstructive sleep apnea syndrome have a beneficial effect on brain oxygenation? Does respiratory muscle training applied to individuals with obstructive sleep apnea syndrome have a beneficial effect on the brain's healing and adaptation processes? A total of 42 individuals with obstructive sleep apnea syndrome will be included in the study. Researchers will compare the effectiveness of respiratory muscle training on individuals with obstructive sleep apnea syndrome by comparing the respiratory muscle training intervention with placebo (low-intensity respiratory muscle training) and usual care. At the beginning of the study, participants' demographic data will be recorded, they will be assessed, their blood will be drawn, and they will be asked to complete a questionnaire. Participants will be given an information brochure and a weekly follow-up form in addition to the necessary medical treatment. Participants will receive the necessary medical treatment for 8 weeks, fill out the follow-up form provided every day and send it to the researcher once a week, perform inspiratory muscle training exercises for 8 weeks, and meet face-to-face with the researcher once a week. The follow-up form will be checked every week. All assessments will be repeated at the end of the study.
Age range
18 Years – 60 Years
Sex
ALL
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Digit Span Test
Timeframe: Baseline and 8 weeks
Montreal Cognitive Assessment Scale
Timeframe: Baseline and 8 weeks
Oktem Verbal Memory Processes Test
Timeframe: Baseline and 8 weeks
Stroop Test
Timeframe: Baseline and 8 weeks
Functional near-infrared spectroscopy (fNIRS)
Timeframe: Baseline and 8 weeks
Verbal fluency test
Timeframe: Baseline and 8 weeks
Brain-Derived Neurotrophic Factor
Timeframe: Baseline and 8 weeks