Comparing Bisoprolol and Valsartan-Amlodipine for Hypertension (NCT07327749) | Clinical Trial Compass
CompletedPhase 4
Comparing Bisoprolol and Valsartan-Amlodipine for Hypertension
Iran59 participantsStarted 2022-10-01
Plain-language summary
Randomized comparison of bisoprolol 2.5 mg monotherapy with fix combination drug valsartan 80 mg- amlodipine 5 mg
Who can participate
Age range30 Years – 59 Years
SexALL
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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* newly diagnosed stage 1 or stage 2 hypertension confirmed by 24-hour ambulatory blood pressure monitoring (ABPM).
Exclusion Criteria:
* Severe hypertension (systolic blood pressure ≥ 180 mmHg or diastolic blood pressure ≥ 110 mmHg)
* Contraindications to beta-blockers
* Contraindication to calcium channel blocker
* Contraindication to angiotensin receptor blockers
* Significant comorbidities requiring specific therapy such as diabetes or chronic heart failure, or current use of medications that could interact with the study drugs were excluded
* Pregnant or breastfeeding women
* Individuals with suspected secondary hypertension, and those unable to adhere to follow-up procedures