Evaluation of Irisin Levels in Adult Forearm Fracture Surgery Under Infraclavicular Block and General Anesthesia

Inclusion Criteria: * Adults aged 18 to 65 years Scheduled for elective forearm fracture surgery Planned to receive either general anesthesia or infraclavicular brachial plexus block American Society of Anesthesiologists (ASA) physical status I-III Able to provide written and verbal informed consent Exclusion Criteria: * Age \<18 years or \>65 years Emergency surgery Refusal or inability to provide informed consent ASA physical status IV or V Known bone diseases or metabolic bone disorders Multiple trauma or associated organ injury Inability to mobilize Morbid obesity (BMI \>40 kg/m²) Renal failure Hepatic failure Neurological deficits or sequelae Contraindication or allergy to any anesthetic agents used in the study