Active — Not RecruitingNot Applicable

Advanced PRF vs PRF for Gap Filling in Immediate Implants

Egypt16 participantsStarted 2025-06-25

Plain-language summary

Study type: Clinical Trial Goal: The goal of this clinical trial is to learn if Advanced Platelet-Rich Fibrin (A-PRF) versus traditional Platelet-Rich Fibrin (PRF) can improve bone healing and soft tissue outcomes in patients undergoing immediate dental implant placement. Main questions it aims to answer: Does A-PRF provide greater buccal bone preservation compared to PRF after immediate implant placement? Does A-PRF improve soft tissue healing and reduce postoperative complications compared to PRF? Comparison group: Researchers will compare A-PRF to PRF as a gap-filling material in immediate implants to see if A-PRF results in better bone and soft tissue outcomes. Participants will: Undergo tooth extraction followed by immediate implant placement Receive either A-PRF or PRF as the gap-filling material in the implant site Have CBCT scans at baseline and 6 months to measure bone thickness Have clinical assessments of soft tissue healing and implant stability Attend follow-up visits at 1 week, 1 month, 3 months, and 6 months post-surgery

Who can participate

Age range20 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * The selected patients has a badly decayed mandibular posterior teeth which are indicated for extraction due to dental causes (periapical abscess, trauma or caries) not periodontal as diagnosed by periapical x-ray. * Healthy patients who are classified according to the American Society of Anesthesiologists (ASA)(2022) physical status classification as class I. * Patient age ≥ 20 years old. * Surgical site with sufficient for implant placement. * Sufficient interocclusal space for prosthesis. * Good oral hygiene. * Patients have thick biotype. * Patients have socket class I. Exclusion Criteria: * Active periodontal diseases and periapical lesions not chronic infections. * Patients have parafunctional * History of alcohol or drug dependency, psychological factor that might affect the surgical or prosthodontic treatment. * Smoking. * Pregnant patients. * Patients who are not willing to complete the study.

What they're measuring

Clinical evaluation

Timeframe: 6 month

Trial details

NCT IDNCT07319494

SponsorBeni-Suef University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2025-11-26