Using TropoCells(R) Autologous Platelet-Rich Fibrin (PRF) to Treat Chronic Non-Healing Wounds

Exclusion criteria

• ✕. Life expectancy is less than twelve (12) months.
• ✕. Participation in another clinical trial involving an investigational device or drug within thirty (30) days prior to enrollment.
• ✕. Sepsis within two (2) weeks prior to enrollment.
• ✕. Soft tissue infection affecting the wound within two (2) weeks prior to enrollment.
• ✕. Known osteomyelitis or occult osteomyelitis documented with inflammatory markers ESR ≥ 60 and/or CRP ≥7.9 mg/dL.
• ✕. Religious constraints to using blood products, including autologous blood.
• ✕. Alcohol or substance abuse (other than tobacco) within 2 months prior.
• ✕. Severe lymphedema at Stage 3b or greater (lymphostatic elephantiasis).