Not Yet RecruitingNot Applicable

Effects of MWM Vs Sustained Mobilization on Knee Osteoarthritis

Pakistan68 participantsStarted 2025-12-30

Plain-language summary

This article focused on people diagnosed with grade III Knee OA with sample size of 68 patients , who will randomly divided into two groups . Group A received Mulligan's MWM while group B received Kaltenborn's Sustained Mobilization along with eccentric exercises. The goal of the study was to compare the effectiveness of these two treatment conditions in reducing knee pain and improving joint function decreasing disability in daily activities. The patients followed a structured treatment plan over a set period and outcomes will measured using reliable clinical tools such as NPRS for pain KOOS for functional disability and Goniometer for ROM.

Who can participate

Age range

45 Years – 70 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: Age between 45 and 70 years Both male and female patients with a history of knee osteoarthritis were selectedfor this study. Clinically and radiologically diagnosed with Grade III Knee Osteoarthritis (basedon Kellgren and Lawrence scale). Meets ACR criteria for knee OA Exclusion Criteria: History of knee or lower limb surgery Received corticosteroid injections (oral or intra-articular) in the past 6 months Other musculoskeletal conditions in the lower limb(e.g., fracture, bursitis, back pain with radiating symptoms) Diagnosed with inflammatory joint diseases (e.g., rheumatoid arthritis, gout) Neurological conditions affecting lower limbs (e.g., stroke, neuropathy) BMI \> 35 (severe obesity) that limits safe participation in exercises Any contraindications to manual therapy (e.g., malignancy, infection, unstablejoint)

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

Pain Intensity

Timeframe: 4 weeks

Functional Disability

Timeframe: 4 weeks

Trial details

NCT IDNCT07315464

SponsorLahore University of Biological and Applied Sciences

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2026-06-30

Contact for this trial

Fakiha Nayab, DPT

03245399916 fakihamughal90@gmail.com

View on ClinicalTrials.gov More Knee Osteoarthritis trials