CompletedNot Applicable

Structural Remodeling of Tibialis Anterior Muscle in Stroke

Turkey (Türkiye)36 participantsStarted 2025-05-01

Plain-language summary

This study aims to investigate the structural architectural changes of the Tibialis Anterior muscle in patients with subacute and chronic stroke using ultrasonography. The study will compare the morphological parameters (pennation angle, fascicle length, and muscle thickness) of the paretic side with the non-paretic side and analyze the relationship between these structural changes and the patients' clinical and demographic data.

Who can participate

Age range

40 Years – 80 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Male and female patients aged 40-80 years. * History of ischemic or hemorrhagic Cerebrovascular Accident (CVA). * Being in the subacute or chronic phase post-stroke. * Absence of communication deficits; ability to follow verbal commands. * Voluntary agreement to participate and provision of written informed consent. * Ability to ambulate without physical assistance from another person (use of assistive devices such as leg orthoses or tripods is permitted). Exclusion Criteria: * Presence of other comorbidities affecting gait (e.g., Parkinson's disease, hip surgery, etc.). * History of dyspnea (shortness of breath) during activities of daily living within the last 6 months. * Presence of bone or joint-related pain or pathology in the spine or hips. * Presence of psychiatric or cognitive disorders (e.g., learning disabilities, mental disorders, autism, etc.). * Decompensated cardiac, renal, or hepatic failure. * Presence of malignancy.

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

Pennation Angle

Timeframe: at baseline assessment

Muscle Thickness

Timeframe: at baseline assessment

Muscle Fascicle Length

Timeframe: at baseline assessment

Trial details

NCT IDNCT07314918

SponsorIstanbul Physical Medicine Rehabilitation Training and Research Hospital

Sponsor typeOTHER_GOV

Study typeOBSERVATIONAL

Primary completion2025-07-01

View on ClinicalTrials.gov More Stroke trials

Plain-language summary

Who can participate

Age range

40 Years – 80 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.