Impact of Interventional Revascularization on the Physiological Assessment of Bystander Coronary Lesions by FFR

Inclusion Criteria: * Age ≥ 18 years * Scheduled percutaneous coronary intervention for at least one coronary lesion (as indicated by evidence of myocardial ischemia on non-invasive stress imaging, an angiographic stenosis severity \>90% diameter stenosis, or an hemodynamically significant intracoronary pressure measurement) * Additional stenosis of ≥ 30% diameter stenosis in a parallel coronary artery anatomically suitable for wire-based intracoronary pressure assessment Exclusion Criteria: * ST-elevation myocardial infarction * Non-ST-elevation myocardial infarction with immediate invasive strategy recommended by current ESC guidelines (e.g. due to hemodynamic instability, cardiogenic shock, acute heart failure presumed secondary to ongoing myocardial ischemia, recurrent or ongoing chest pain refractory to medical treatment, or life-threatening arrhythmias or cardiac arrest after presentation) * Acute totally occluded coronary artery * Unsuitability for intracoronary measurement of FFR (e.g. due to contraindications for the administration of adenosine)