Aspergillus fumigatus PCR is currently used in conjunction with serum galactomannan to support the diagnosis of invasive aspergillosis or for monitoring at-risk patients not receiving antifungal prophylaxis. A positive result and a high titer are thought to be associated with the advanced stage of the disease and the fungal load. However, there is limited data on this subject, and no study has primarily focused on the variation of PCR levels during treatment and its potential correlation with treatment efficacy.
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Death rate at day 30 in patients with a positive follow-up PCR (blood or bronchoalveolar lavage)
Timeframe: Day 30 post-antifungal treatment
baptiste Hoellinger, MD