Effectiveness of Combined Fascial Plane Blocks for Postoperative Pain in Gynecologic Oncology Sur… (NCT07312825) | Clinical Trial Compass
CompletedNot Applicable
Effectiveness of Combined Fascial Plane Blocks for Postoperative Pain in Gynecologic Oncology Surgery
Turkey (Türkiye)94 participantsStarted 2024-01-01
Plain-language summary
The goal of this prospective observational study is to compare the effectiveness of different postoperative analgesic techniques in patients undergoing major abdominal surgery for gynecologic oncology.
The main question is whether the combination of TAP block with Quadratus Lumborum Block (QLB) or Rectus Sheath Block (RSB) provides superior pain relief compared to TAP block alone.
All blocks were performed as part of routine clinical anesthesia practice according to the attending anesthesiologist's judgment. No randomization, allocation, or study-directed intervention was performed.
Patients were classified into three groups based on the block type they received during standard care:
Group 1: TAP Block Only
Group 2: TAP + QLB Combination
Group 3: TAP + RSB Combination
Postoperative data, including pain scores (VAS), opioid consumption, sedation level, heart rate, blood pressure, nausea/vomiting, and length of hospital stay, were collected prospectively.
The study aims to determine which block combination provides the best postoperative pain control and recovery profile in patients undergoing gynecologic oncology surgery.
Who can participate
Age range
18 Years
Sex
FEMALE
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria
* Age 18 years or older.
* ASA physical status I-IV.
* Scheduled for major gynecologic oncology surgery (endometrial cancer, ovarian tumor, or cytoreductive surgery).
* Undergoing general anesthesia.
* Planned postoperative abdominal fascial plane block for pain management (TAP, TAP + QLB, or TAP + RSB).
* Able to provide written informed consent.
Exclusion Criteria
* Refusal to participate or inability to provide informed consent.
* Emergency surgery.
* Known allergy or contraindication to local anesthetics.
* Infection at the block site.
* Coagulopathy or anticoagulant use that contraindicates regional anesthesia.
* Pre-existing chronic pain conditions or chronic opioid use.
* Severe hepatic or renal insufficiency.
* Cognitive impairment that prevents reliable pain assessment.
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Total Morphine Consumption
Timeframe: Within 24 hours after surgery
Trial details
NCT IDNCT07312825
SponsorDr Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital