To manage the treatment in the intensive care unit for patients with septic shock, central venous oxygen saturation (scvO2) is used as a macrocirculatory indicator, with a target value of 70% or higher being recommended. Tissue oxygenation (stO2) measurement can be implemented to assess the microcirculation in these patients, but a specific target value has not been established yet. The investigators believe that guiding the treatment of septic shock patients based on the measurement of microcirculation using stO2 and evaluating its correlation with scvO2 can reduce mortality. This study aims to investigate the independent impact of high-dose norepinephrine on microvascular reactivity assessed by NIRS-VOT in patients with septic shock, while also examining how these microcirculatory indices relate to the macrocirculatory marker ScvOâ‚‚.
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Central Venous Oxygen Saturation (ScvOâ‚‚) Level
Timeframe: Baseline (first 1 hour)
Norepinephrine Equivalent Vasopressor Dose
Timeframe: Baseline (first 1 hour)
Baseline Tissue Oxygen Saturation (stOâ‚‚_baseline)
Timeframe: Within 1 hour of enrollment
Minimum Tissue Oxygen Saturation During Vascular Occlusion (stOâ‚‚_min)
Timeframe: Within 1 hour of enrollment
Maximum Tissue Oxygen Saturation After Reperfusion (stOâ‚‚_max)
Timeframe: Within 1 hour of enrollment
Recovery Time (From stOâ‚‚_min to stOâ‚‚_max)
Timeframe: Within 1 hour of enrollment