CompletedNot Applicable

Evaluation of Mirabegron Versus Tamsulosin or Their Combination in Treatment of Lower Urinary Tract Symptoms

Egypt300 participantsStarted 2024-10-10

Plain-language summary

Stent related symptoms (SRSs) comprise of complaints such as irritative symptoms, sense of incomplete emptying, flank and suprapubic pain, and incontinence. Mechanical irritation of trigone, urinary reflux, and stent movement are plausible causes for SRSs. Alpha-blockers are the primary medications for ureteral stent-related symptoms. These medications are suggested to patients by the American Urological Association (AUA)/Endourological Society guideline to reduce stent-related symptoms with moderate recommendation. Nevertheless, there are many side effects associated with alpha-blockers such as dizziness, headache, and orthostatic hypotension

Who can participate

Age range18 Years – 50 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * First time to use Ureteric stent . Exclusion Criteria: * Urinary tract infection. * Previous ureteral surgery. * Congenital malformation of the ureter. * Distal ureteric stricture. * Hypersensitivity to the drugs. * Pregnancy or lactation. * Hepatic insufficiency * Non-compliant patients. * Age \< 18 years old .

What they're measuring

Treatment of Ureteral Stent Pain

Timeframe: 4 Weeks

Trial details

NCT IDNCT07307261

SponsorAvraiem Talaat

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2025-10-05

View on ClinicalTrials.gov More Ureteric Stent-related Morbidity trials