RecruitingNot Applicable

Virtual Lesion Segmentation and Mandibular Ameloblastoma Radiographic Safety Margin

Egypt10 participantsStarted 2025-01-01

Plain-language summary

Reconstruction of segmental mandibular defects is in a continuous state of evolution utilizing the recent advances in Computer-Aided Designing (CAD) and preoperative Virtual Surgical Planning (VSP). The anterior iliac crest is one of the ideal reservoirs for autogenous harvesting of a bi-cortical bone block with 1:1 cortical to cancellous bone ratio which is optimal for rapid and predictable consolidation. The aim of this study is the utility of VSP guided by CT and confirmation by histopathological analysis in achieving negative margins and preventing recurrence of mandibular ameloblastoma.

Who can participate

SexALL

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Inclusion criteria

✓. Patients with histologically confirmed ameloblastoma using a preoperative biopsy.
✓. Patients with ameloblastoma that require segmental mandibular continuity defect, not involving the condyle.

Exclusion criteria

✕. Patients with lateral segmental mandibular defect involving the condyle.
✕. Patients with an active infection at the site of resection.
✕. Patients with recurrent lesion after resection.

What they're measuring

Histological analysis and degree of lesion invasion determination

Timeframe: 1 month

Trial details

NCT IDNCT07306962

SponsorAlexandria University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2026-12-01

Contact for this trial

yehia A El-Mahallawy., PhD

+201007217014. yehia.el-mahallawy@alexu.edu.eg

View on ClinicalTrials.gov More Ameloblastoma trials