CompletedNot Applicable

PCV vs VCV in Low-Flow Anesthesia

Turkey (Türkiye)40 participantsStarted 2023-07-01

Plain-language summary

The aim of this observational study is to investigate the effects of ventilation modes on intraoperative and postoperative lung functions in patients under general anesthesia. This study aimed to compare the effects of low-flow anesthesia on intraoperative respiratory mechanics and early postoperative pulmonary function between PCV and VCV in ASA I-II adult patients.

Who can participate

Age range18 Years – 65 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: \- age 18-65 years and American Society of Anesthesiologists (ASA) physical status I-II. Exclusion Criteria: * morbid obesity (BMI \> 35 kg/m²), * scoliosis or thoracic deformity, * restrictive or obstructive lung disease, * prior thoracic or upper abdominal surgery, * history of major thoracic trauma or congenital chest wall anomaly, * active smoking or chronic use of corticosteroids, * β-agonists, bronchodilators, or antihistamines, * anticipated difficult airway * severe hypoxemia (SpO₂ \< 90%) during induction.

What they're measuring

Mean Ppeak (cmH₂O) at each time point; between-group difference.

Timeframe: From post-intubation baseline until 30 minutes after initiation of low-flow anesthesia (approximately 45 minutes total).

Trial details

NCT IDNCT07305129

SponsorHULYA TOPCU, MD

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2024-07-15

View on ClinicalTrials.gov More ASA Class I/II Patients trials