Not Yet RecruitingNot Applicable

Center M Randomized Trial

160 participantsStarted 2025-12

Plain-language summary

This is a randomized controlled trial with an intervention of Center M compared to treatment as usual. Center M consists of weekly digital one-hour group sessions led by a trained therapist aligned with mindfulness based cognitive therapy. Changes in perinatal depression symptoms will be compared between groups.

Who can participate

Age range18 Years

SexFEMALE

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Currently pregnant at ≥ 12 weeks of gestation age (GA) * ≤ 34 weeks GA at time of Center M intervention initiation * Receiving prenatal care through the Center for Women's Health at Oregon Health \& Science University * Able to fluently understand, speak and read English * Available, able and willing to attend online group sessions * Willing and able to receive home practice materials on an accessible smartphone, tablet or computer * Residing in Oregon or Washington * Willingness to participate in either randomization arm Exclusion Criteria: * Current or past enrollment in a formal mindfulness-based intervention group * Score in the "severe" range on the Edinburgh Postnatal Depression Scale (EPDS) (≥ 20) or Patient History Questionnaire (PHQ-9) (≥ 20)

What they're measuring

Change in EPDS scores (baseline to 6 weeks)

Timeframe: Difference between baseline and 6 weeks postpartum

Change in PHQ scores (baseline to 6 weeks)

Timeframe: Difference between baseline and 6 weeks postpartum

Trial details

NCT IDNCT07304895

SponsorOregon Health and Science University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2026-12

View on ClinicalTrials.gov More Perinatal Depression trials