Following oncolytic virus (OV) administration, the host immune response is initiated immediately and evolves dynamically. However, in clinical OV therapy, it is virtually impossible to capture these immune events in real time. To address this gap, the principal investigator conducted a high-resolution immune monitoring study in a healthy volunteer.
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Changes in ANC(absolute neutrophil count) over time
Timeframe: 4 hour, 8 hour, 20 hour, 24 hour, Day 2, Day 5, Day 8, Day 16
Changes in lymphocytes count over time
Timeframe: 4 hour, 8 hour, 20 hour, 24 hour, Day 2, Day 5, Day 8, Day 16