Not Yet RecruitingNot Applicable

Velopharyngeal Insufficiency After Maxillomandibular Advancement Osteotomy in Obstructive Sleep Apnea Patients

Netherlands28 participantsStarted 2026-05-01

Plain-language summary

The aim of this study is to gain insight into the development of velopharyngeal insufficiency (VPI) in patients who have undergone maxillomandibular advancement osteotomy (MMA) as a treatment for obstructive sleep apnea syndrome (OSAS). A speech therapist evaluates nasality, speech, and swallowing before and after the surgery.

Who can participate

Age range18 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Age \> 18 years * Mild to severe OSA * Indication for MMA for OSA treatment Exclusion Criteria: * patients who underwent other adjunctive procedures at the time of MMA (e.g., multipiece le Fort osteotomy, TMJ reconstruction * Previous history of orthognathic surgery * Previous history of orthognathic surgery * Previous history of oropharyngeal surgery (UPPP or multi-level surgery) * Cleft palate and syndromic patients * Neuromusculair diseases which causes VPI, dysphagia or dysarthria * Incapacity

What they're measuring

Nasality

Timeframe: Timpoints: T0 preoperative, T1 6 weeks after surgery, T2 3 months after surgery, T3 6 months after surgery, T4 1 year after surgery

Trial details

NCT IDNCT07301021

SponsorAcademisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2027-12-01

Contact for this trial

Misha Tan, PhD student

+31613125803 m.l.tan@amsterdamumc.nl

View on ClinicalTrials.gov More Velopharyngeal Insufficiency trials