Not Yet RecruitingNot Applicable

Cognitive Behavior Therapy Among Patients With Major Depressive Disorder-Multiple Episodes.

Pakistan80 participantsStarted 2026-01

Plain-language summary

The main purpose of this study to teach the patients how to manage their depression, generalized Anxiety symptoms, mental health seeking attitude, motivation and attitude toward changing health, to improve the quality of life, and meta memory and meta cognitive functioning after using Adapted CBT. Enhance emotional regulation by helping patients identify and modify maladaptive emotional responses, thereby reducing emotional reactivity and promoting healthier coping strategies. Strengthen relapse prevention skills by equipping patients with long-term cognitive and behavioral techniques to recognize early warning signs and apply learned strategies proactively to prevent future episodes. This research would be helpful for patients etc.

Who can participate

Age range

18 Weeks – 50 Weeks

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Age range: 18-50 years No physical, psychiatric, or psychological conditions. patients who meet multiple Episodes. who meet DSM 5 TR Major Depressive Disorder Criteria. patients who meet moderate severity at patient health questionnaire scale . Exclusion Criteria: * age range: below 18 and above 50 years. presence of any physical, psychiatric, or psychological conditions. who do not meet DSM 5 TR Major Depressive Disorder Criteria. range at patient health questionnaire scale is mild , minimal or severe or moderately severe.

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

Patient Health Questionnaire PHQ-9 (Kroenke, and colleagues, 1999)

Timeframe: at pre-Assessment, after 5 weeks at post-Assessment

Generalized Anxiety Disorder 7-item scale (GAD-7)

Timeframe: at Pre-Assessment, after 5 weeks at post-Assessment

WHOQOL BREF Scale (WHO; Skevington, Lotfy &Connell, 2004).

Timeframe: at pre-assessment, after 5 weeks at post-assessment

Mental Help-Seeking Attitudes Scale (MHSAS),

Timeframe: at pre-assessment, after 5 weeks at post-assessment

Motivation and Attitudes Toward Changing Health (MATCH)

Timeframe: at pre-assessment, after 5 weeks at post-assessment

Digit Span Test ( Backward and Forward)

Timeframe: at pre-assessment, after 5 weeks, post-assessment

Trial details

NCT IDNCT07300527

SponsorGovernment College University Faisalabad

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2026-07-31

Contact for this trial

Qasir Abbas Dr, PhD Clinical Psychology

923337683133 qasirabbas47@yahoo.com

View on ClinicalTrials.gov More Patients With Major Depressive Disorder trials

Plain-language summary

Who can participate

Age range

18 Weeks – 50 Weeks

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

What they're measuring

Patient Health Questionnaire PHQ-9 (Kroenke, and colleagues, 1999)

Timeframe: at pre-Assessment, after 5 weeks at post-Assessment

Generalized Anxiety Disorder 7-item scale (GAD-7)

Timeframe: at Pre-Assessment, after 5 weeks at post-Assessment

WHOQOL BREF Scale (WHO; Skevington, Lotfy &Connell, 2004).

Timeframe: at pre-assessment, after 5 weeks at post-assessment

Mental Help-Seeking Attitudes Scale (MHSAS),

Timeframe: at pre-assessment, after 5 weeks at post-assessment

Motivation and Attitudes Toward Changing Health (MATCH)

Timeframe: at pre-assessment, after 5 weeks at post-assessment

Digit Span Test ( Backward and Forward)

Timeframe: at pre-assessment, after 5 weeks, post-assessment