Active — Not RecruitingNot Applicable

Virtual Reality-Assisted Intraoperative Sensory Modulation on Postpartum Depression and the Kynurenine Pathway

Turkey (Türkiye)98 participantsStarted 2025-10-01

Plain-language summary

The research will be conducted as a prospective, observational, and comparative study with 98 pregnant volunteers aged 18-45 at Düzce University Faculty of Medicine. Participants will be divided into a VR group and a control group. Data will be collected using STAI-I, EPDS, NRS scales, and biochemical analyses (tryptophan, kynurenine, etc.). Upon completion, the project is expected to contribute to non-pharmacological approaches and new care protocols for reducing postpartum depression.

Who can participate

Age range18 Years – 45 Years

SexFEMALE

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Pregnant women scheduled for elective cesarean section * Age between 18 and 45 years * ASA physical status I-II * No contraindication to spinal anesthesia * Accepted for VR equipment usage during operation. * Signed written informed consent Exclusion Criteria: * Anticipated need for postoperative intensive care unit (ICU) admission * History of psychiatric or neurological disease * Visual or auditory impairment * Severe preeclampsia, eclampsia, or HELLP syndrome * Perinatal loss (postpartum neonatal death) * History of convulsions or epilepsy

What they're measuring

Change in Edinburgh Postnatal Depression Scale (EPDS)

Timeframe: up to 6 weeks

Change in State-Trait Anxiety Inventory-State (STAI-I) score

Timeframe: up to 6 weeks

Trial details

NCT IDNCT07300176

SponsorDuzce University

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2026-10-01

View on ClinicalTrials.gov More Virtual Reality trials