Blocking Sphenopalatine Ganglion by Intranasal Lidocaine Spray in Partial Turbinectomy Surgeries (NCT07299630) | Clinical Trial Compass
CompletedPhase 3
Blocking Sphenopalatine Ganglion by Intranasal Lidocaine Spray in Partial Turbinectomy Surgeries
Egypt50 participantsStarted 2025-12-20
Plain-language summary
Nasal turbinectomy surgeries are usually done as day case surgeries as most patients are young with unremarkable comorbidities. However, considerations are still present towards patients of old age or those suffering from obesity or obstructive sleep apnea (OSA). Different techniques are still evolving to improve handling those patients to decrease complications, enhance recovery after surgery and increase patient satisfaction. Targeting sphenopalatine ganglion block by topical local anesthesia is a proposed technique that could help by decreasing peri-operative opioid consumption.
Who can participate
Age range
18 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Undergoing elective partial turbinectomy surgery
* Age 18 years or older
Exclusion Criteria:
* Patient refusal
* Kidney or liver impairment
* Pregnant or breast-feeding women
* Allergy to any of the drugs used in the study
* OR time more than 90 minutes (defined as time after anaesthesia induction and securing Endotracheal tube to end of surgery, excluding extubation time)
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1This trial looked at blocking the sphenopalatine ganglion with a lidocaine nasal spray during partial turbinectomy surgery — could that approach reduce how much fentanyl I might need for pain control during my own procedure?
2Since this was a Phase 3 trial and it's now completed, has the data been published yet, and what did it actually show about whether the lidocaine spray block worked compared to not using it?
3The trial measured fentanyl doses as its main outcome — does that mean the main goal was reducing opioid use during surgery, and if so, how might that affect my recovery or how I feel after the operation?
4Is a sphenopalatine ganglion block with intranasal lidocaine something you already use or would consider using during my turbinate surgery, based on what this trial found?
5Are there any patients for whom this type of nerve block might not be appropriate or safe — for example, because of certain medications, allergies to lidocaine, or the specific extent of their turbinate surgery?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.