ORCHARDS-AIR Study (NCT07298967) | Clinical Trial Compass
SuspendedNot Applicable
ORCHARDS-AIR Study
Stopped: for the summer, continue enrollment this fall
United States422 participantsStarted 2026-01-07
Plain-language summary
The purpose of this observational study is to compare the effectiveness of air surveillance and to better understand the relationship between household transmission and viruses detected in the air.
Participants will provide nasal swabs and have an air sample surveillance device installed in their home.
Who can participate
Age range
4 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria - Students:
* Student attends, or is eligible to attend, a school within the Oregon School District (OSD)
* Study has an illness characterized by at least 2 of 6 acute respiratory infection (ARI)/ILI symptoms (nasal discharge, nasal congestion, sneezing, sore throat, cough, fever) and student scores at least 2 points on the Jackson scale
Exclusion Criteria - Students:
* Household member listed on Wisconsin Department of Corrections Sex Offender Registry
* Illness onset more than 7 days before anticipated time of specimen collection
* Anatomical defect for which nasal specimen collection is contraindicated
* Student participated too recently (\<7 days from day 14 during peak influenza / COVID-19 period and \<30 days during other times, as determined by a medically-attended surveillance program)
Inclusion Criteria - Household member:
* Live in the same household as eligible student participant
* Any age and gender
* Fluent in English
* Able to provide appropriate consent or assent
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Rate of virus detection
Timeframe: Day 0, Day 7, Day 14
2
Rate of air sampling detection among families with documented transmission
Timeframe: Day 7, Day 14
3
Rate of air sampling detection among families without documented transmission