ORCHARDS-AIR Study

Inclusion Criteria - Students: * Student attends, or is eligible to attend, a school within the Oregon School District (OSD) * Study has an illness characterized by at least 2 of 6 acute respiratory infection (ARI)/ILI symptoms (nasal discharge, nasal congestion, sneezing, sore throat, cough, fever) and student scores at least 2 points on the Jackson scale Exclusion Criteria - Students: * Household member listed on Wisconsin Department of Corrections Sex Offender Registry * Illness onset more than 7 days before anticipated time of specimen collection * Anatomical defect for which nasal specimen collection is contraindicated * Student participated too recently (\<7 days from day 14 during peak influenza / COVID-19 period and \<30 days during other times, as determined by a medically-attended surveillance program) Inclusion Criteria - Household member: * Live in the same household as eligible student participant * Any age and gender * Fluent in English * Able to provide appropriate consent or assent