CompletedNot Applicable

Efficacy of Er:YAG Laser in Removing Impacted Mandibular Third Molars

Egypt24 participantsStarted 2024-09-25

Plain-language summary

This randomized controlled clinical trial aims to evaluate the efficacy of the Er:YAG laser in the removal of impacted mandibular third molars compared to the conventional surgical technique. The study assesses surgical efficiency, postoperative pain, swelling, trismus, and overall patient recovery. The goal is to determine whether the Er:YAG laser provides a safer and less traumatic alternative to traditional bone-cutting methods during third molar surgery.

Who can participate

Age range

18 Years – 30 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * • Adults aged 20-30 years requiring surgical extraction of a mesioangular impacted mandibular third molar. * Healthy individuals with no systemic diseases that may influence bone metabolism or wound healing. * Good oral hygiene and absence of local infection at the surgical site. * No contraindications to local anesthesia, surgical extraction, or use of the Er:YAG laser. * Radiographic evidence confirming normal bone structure without cysts or pathological lesions. * Willingness to participate and ability to provide informed consent. Exclusion Criteria: * • Systemic medical conditions affecting bone healing or postoperative response (e.g., uncontrolled diabetes, immunodeficiency, metabolic bone disorders). * Current or recent use of medications influencing bone remodeling (e.g., bisphosphonates, corticosteroids, immunosuppressants). * Heavy smoking (\>10 cigarettes/day). * Pregnant or breastfeeding females. * Poor oral hygiene, active infection, or pericoronitis at the surgical site. * Previous surgery, trauma, or pathology in the mandibular third molar region. * Known allergies or contraindications to any material or procedure used in the study.

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

Postoperative Pain Score

Timeframe: Immediate postoperative, 24 hours, 3 days, and 7 days

Trial details

NCT IDNCT07297043

SponsorAlexandria University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2025-01-15

View on ClinicalTrials.gov More Impacted Mandibular Third Molar trials