An Artificial Intelligence Driven Approach to Optimize Patient Selection for a Transitional Pain … (NCT07296770) | Clinical Trial Compass
Not Yet RecruitingPhase 3
An Artificial Intelligence Driven Approach to Optimize Patient Selection for a Transitional Pain Service
United States126 participantsStarted 2026-10-01
Plain-language summary
The goal of this clinical trial is to learn whether a pain-management program called a Transitional Pain Service can help prevent long-term pain and reduce opioid needs after surgery in adult surgical patients who may be at higher risk for developing persistent pain. The main questions this trial aims to answer are: 1) Does the Transitional Pain Service help high-risk surgical patients manage pain better after surgery? 2) Can a computer tool (an algorithm) improve screening of patients for long-lasting pain after surgery? The investigators will compare patients who continue with their usual care to patients who receive support from the Transitional Pain Service to see if the program leads to better pain control and lower opioid use. Participants will share information about their pain levels and the pain-relief treatments they are using before and after surgery so researchers can better understand how the program affects recovery. Patients assigned to the Transitional Pain Service will also be offered additional coordinated support before and after their surgery to help optimize their pain control and overall recovery.
Who can participate
Age range
18 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Patients may take part in this study if they:
* Are 18 years or older
* Are having a planned (elective) surgery at UCSF
* Are identified as higher risk for chronic pain after surgery by a computer model
* Agree to join the study and sign consent
Patients cannot take part if they:
* Have too much missing information in their medical record (more than 75%)
* Have a surgery scheduled less than 1 month away
* Have serious memory or thinking problems that make participation difficult
* Are in another clinical study that would interfere with this one
* Do not live in California
* Choose not to participate or sign consent
* Have severe depression with suicidal thoughts that requires urgent care
* Are pregnant or breastfeeding
A patient who has already joined may be removed from the study if they:
* Cannot complete most of the scheduled follow-up phone calls or pre-surgery recommendations (up to 6 months after discharge)
* Pass away between the surgery booking date and 6 months after leaving the hospital
* Become pregnant in the 6 months after discharge
Patients may remain enrolled but their data may not be used in the main study results if they experience:
* A long-lasting infection after surgery
* Hardware problems related to their surgery (for example, issues with implanted devices)
* A major injury or life event that affects their pain levels, such as a significant fall or an emergency surgery
* Difficulty completing the planned follow-up phone calls up to 6 months after d…
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Proportion of Patients With Chronic Post-Surgical Pain