By InvitationNot Applicable

Expert Consensus on the Use of Isotretinoin in Rejuvenation: A Delphi Study

Egypt15 participantsStarted 2026-01-25

Plain-language summary

This expert consensus project explores the role of low-dose isotretinoin as a rejuvenative and preventive strategy for photoaging and sebaceous-driven skin changes. While isotretinoin is traditionally used for acne, increasing clinical experience suggests that carefully selected micro-dose and low-dose regimens may improve skin texture, pore size, sebaceous activity, and overall skin quality, with potential benefits in skin aging and maintenance rejuvenation programs.

Who can participate

SexALL

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Inclusion Criteria: * Board-certified dermatologists or equivalent. * 5 years clinical experience in dermatology. Practical experience prescribing isotretinoin, including low- or micro-dose regimens for rejuvenation or acne. Active engagement in clinical dermatology, teaching, research, or guideline development. Willingness to participate in all Delphi rounds and provide informed consent. Exclusion Criteria: * Non-dermatology specialists. Less than 5 years of clinical experience. Lack of relevant isotretinoin experience. Significant undisclosed conflict of interest with isotretinoin manufacturers. Inability to participate in all Delphi rounds.

What they're measuring

Primary Outcome

Timeframe: 6-12 weeks

Trial details

NCT IDNCT07296536

SponsorVenus Research Center

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2027-06-01

View on ClinicalTrials.gov More Isotretinoin trials