CompletedNot Applicable

Peripheral Relative Refractive Power of Orthokeratology Lenses

China53 participantsStarted 2020-01-10

Plain-language summary

Orthokeratology (OK) has been demonstrated to be an effective intervention for slowing axial elongation in children with myopia. The proposed mechanism of action is the induction of peripheral myopic defocus, which reduces relative peripheral hyperopia on the retina. This study aims to evaluate changes in relative peripheral retinal refraction before and after OK lens wear using wide-field multispectral retinal refractive topography. The study will also investigate the relationship between these retinal refractive changes and the effectiveness of OK in controlling axial elongation.

Who can participate

Age range8 Years – 15 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * 8 to 15 years old * myopia of -4.00D or lower, * regular astigmatism ≤1.50D and non-regular astigmatism ≤1.00D * intraocular pressure ≤21mmHg * understand the purpose of the study and have good hygiene and regular follow-up Exclusion Criteria: * unilateral * immunocompromised subjects with systemic diseases (such as acute or chronic sinusitis, diabetes mellitus, Down syndrome, rheumatoid arthritis, psychiatric patients, etc.) * complicated with other eye diseases that affect OK lens wearing, such as dacryocystitis, blepharitis and other inflammation, glaucoma, etc. * BCVA less than 1.0 * children with corneal curvature less than 40.00D or higher than 46.00D.

What they're measuring

Changes in axial length growth(ALG)

Timeframe: Change from baseline in axial length at 12 months

Trial details

NCT IDNCT07294404

SponsorTianjin Eye Hospital

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2021-06-15

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