Not Yet RecruitingNot Applicable

Doppler Evaluation for Congestive Acute Kidney Injury in Critical Illness

United States100 participantsStarted 2026-07-01

Plain-language summary

This study will evaluate the use of the Venous Excess Ultrasound (VExUS) score to guide fluid management in critically ill ICU patients through a prospective, multi-aim design combining observational and randomized components. The study will be conducted in the medical intensive care unit (MICU), multidisciplinary critical care unit (MCCU), and cardiac care unit (CCU) at UAB.

Who can participate

Age range18 Years

SexALL

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Inclusion Criteria: * Adults (≥18 years old) * Admitted to the MICU, MCCU, or CCU within 24 hours of admission * Acute kidney injury (AKI) (based on Kidney Disease: Improving Global Outcomes (KDIGO) criteria) * Adequate acoustic windows for a complete VExUS scan Exclusion Criteria: * \< 18 years old * pregnant women * End-stage renal disease (ESRD) or prior renal transplant * Acute tubular necrosis (ATN) defined by urinalysis (≥2+ protein, ≥2+ blood, ≥1 muddy brown cast, ≥1 RBC cast, or ≥1 dysmorphic RBC)' * Prior Whipple procedures * currently incarcerated

What they're measuring

In-hospital Mortality

Timeframe: up to 30 days

Renal Replacement Therapy

Timeframe: up to 30 days

Persistent Renal Dysfunction

Timeframe: up to 30 days

Trial details

NCT IDNCT07291778

SponsorUniversity of Alabama at Birmingham

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2027-07-01

Contact for this trial

Timothy I Kennell, MD, PhD

2059965864 tkennell@uabmc.edu

View on ClinicalTrials.gov More Acute Kidney Injury trials