PENG Block vs Suprainguinal FICB vs Lumbar ESPB for Analgesia After Hip Surgery (NCT07288983) | Clinical Trial Compass
RecruitingNot Applicable
PENG Block vs Suprainguinal FICB vs Lumbar ESPB for Analgesia After Hip Surgery
Poland93 participantsStarted 2026-02-06
Plain-language summary
This randomized, double-blinded, controlled clinical trial compares three motor-sparing regional anesthesia techniques used for postoperative analgesia in patients undergoing hip arthroplasty: the Pericapsular Nerve Group (PENG) block, the suprainguinal Fascia Iliaca Compartment Block (S-FICB), and the Lumbar Erector Spinae Plane Block (L-ESPB). Although all three techniques are widely used in modern hip surgery, their relative analgesic efficacy, opioid-sparing potential, and impact on early functional recovery have not been directly compared in a single study.
The primary objective is to determine which block provides the most effective postoperative analgesia while preserving motor function and facilitating early mobilization. Secondary objectives include comparisons of opioid consumption, pain scores at rest and during movement, time to first rescue analgesia, block-related adverse events, quadriceps strength, incidence of postoperative nausea and vomiting, and early functional outcomes.
This study aims to identify the optimal motor-sparing regional anesthesia strategy for older adults undergoing hip arthroplasty.
Who can participate
Age range
65 Years – 100 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Adults aged 65 years or older scheduled to undergo elective hip arthroplasty under spinal anesthesia.
* Ability to provide written informed consent.
* Ability to understand and reliably use numerical pain assessment tools (NRS 0-10).
* ASA physical status II-III.
* Expected postoperative hospitalization of at least 48 hours to ensure complete data collection.
Exclusion Criteria:
* Inability to provide informed consent due to cognitive impairment, language barrier, or severe hearing/speech limitations.
* Coagulopathy or therapeutic anticoagulation not meeting safety criteria for regional anesthesia.
* Local infection at the planned block site.
* Allergy, hypersensitivity, or contraindication to ropivacaine, local anesthetics, or study medications.
* Pre-existing lower-limb neurological deficits (motor or sensory) affecting outcome assessments.
* Severe spinal deformity or anatomical limitations preventing safe performance of regional blocks.
* Chronic opioid use (defined as \>30 mg oral morphine equivalents daily for more than 2 weeks).
* Severe renal failure (eGFR \<30 mL/min/1.73m²) or severe hepatic impairment.
* Uncontrolled diabetes mellitus (fasting glucose \>300 mg/dL or HbA1c \>10%).
* History of local anesthetic systemic toxicity (LAST).
* Participation in another interventional clinical trial within the past 30 days.
* Any condition deemed by investigators to interfere with protocol adherence, safety monitoring, or outcome reliability.
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Total Opioid Consumption in the First 48 Hours After Surgery