Not Yet RecruitingNot Applicable

Extracorporeal Therapy and Therapeutic Drug Monitoring

Italy40 participantsStarted 2025-12-12

Plain-language summary

The aim of this study is to comparatively evaluate serum concentrations of continuously applied antibiotics in ICU patients, with and without ECMO/RRT support.

Who can participate

Age range18 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * adult patients (age 18y or older) * admitted to ICU * supported or not-supported with extracorporeal membrane oxygenation (ECMO) and/or renal replacement therapy (RRT) * affected by gram-negative bacterial infections susceptible to the novel antibiotics. Exclusion Criteria: * Pediatric age (\<18y) * allergies to pharmaceutical and/or inactive drug ingredients (excipients) * life expectancy less than 1 month * body mass index (BMI) \>45 kg/m2 * pregnancy

What they're measuring

Primary aim

Timeframe: up to 24 months

Trial details

NCT IDNCT07287813

SponsorFondazione IRCCS Policlinico San Matteo di Pavia

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2027-01

Contact for this trial

Simona De Gregori

+39 0382503647 s.degregori@smatteo.pv.it

View on ClinicalTrials.gov More ICU Patients With ECMO And-or RRT and With Gram Negative Infections Susceptible to BL-BLIs trials