Not Yet RecruitingNot Applicable

Non-invasive Intracranial Pressure Monitoring in Brain Tumor Patients

Egypt60 participantsStarted 2026-01

Plain-language summary

This research protocol focuses on the pre- and post-operative evaluation of ICP using non-invasive methods, particularly in the context of surgery for brain tumor removal. By utilizing ocular ultrasound to measure ONSD and ONSD/ETD ratios, this study hypothesizes that the utility of these parameters in monitoring ICP pre- and post-operative periods could be effective.

Who can participate

Age range21 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * • Adult patients (\>21 years) undergoing brain tumor resection surgery. * Preoperative imaging-confirmed diagnosis of the tumor. * American Society of Anesthesiologists (ASA) physical status II to IV * Consent to participate in the study. Exclusion Criteria: * • Preexisting ocular conditions affecting the optic nerve or globe integrity, such as glaucoma, thyroid-associated ophthalmopathy, or other optic nerve diseases. * Combined ocular and optic nerve injuries at admission. * History of cranial trauma, prior neurosurgery, or lumbar puncture performed within 2 weeks before the measurement of optic nerve sheath diameter (ONSD). * History of subarachnoid hemorrhage (SAH). * Serious complications that could affect life expectancy, such as hematological disorders or malignancies. * Refusal to participate or withdrawal of consent at any stage.

What they're measuring

optic nerve sheath diameter dynamics

Timeframe: before (in the preoperative holding area) and after the surgery (immediate, 1,2, 4, 6, and 12 hr in ICU).

Trial details

NCT IDNCT07286396

SponsorTanta University

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2026-12

Contact for this trial

tarek AH Mostafa

01003591332 dr.tarek311@yahoo.com