CompletedNot Applicable

Investigation of Antibacterial Effect of Levobupivacaine on Staphylococcus Aureus

40 participantsStarted 2010-11

Plain-language summary

This experimental in vitro study aimed to investigate the antibacterial effect of levobupivacaine on Staphylococcus aureus in a patient-controlled analgesia (PCA) model at concentrations commonly used for postoperative pain treatment (0.125%) and painless labour (0.0625%). The antibacterial activity was evaluated using colony count reduction and supported by Scanning Electron Microscope (SEM) imaging.

Who can participate

SexALL

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Inclusion Criteria: * Laboratory study using Staphylococcus aureus bacterial cultures. * Samples exposed to different concentrations of levobupivacaine and fentanyl solutions. * Controlled laboratory environment (Dokuz Eylül University, Microbiology Laboratory). Exclusion Criteria: * No human participants included. * No animal models used. * Studies outside the defined experimental conditions were excluded.

What they're measuring

Reduction in Staphylococcus aureus Colony Count

Timeframe: 24 hours

Trial details

NCT IDNCT07285759

SponsorDokuz Eylul University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2011-02

View on ClinicalTrials.gov More Staphylococcus Aureus Bacterial Contamination trials